ChemistryCode 9701

Amides

What this topic asks you to be able to do

  • recall the reactions, along with their reagents and conditions, through which amides are formed: (a) ammonia reacting with an acyl chloride, kept at room temperature (b) a primary amine reacting with an acyl chloride, kept at room temperature
  • describe the reactions of amides: (a) hydrolysis using either aqueous acid or aqueous alkali (b) LiAlH₄ reducing the CO group to give an amine
  • state and explain why an amide is a much weaker base than an amine