ChemistryCode 9701

Primary and secondary amines

What this topic asks you to be able to do

  • state the reagents and conditions needed to make primary and secondary amines in each of these cases: (a) halogenoalkanes heated with NH₃ in ethanol under pressure (b) halogenoalkanes heated with primary amines in ethanol in a sealed tube or under pressure (c) amides reduced by LiAlH₄ (d) nitriles reduced by LiAlH₄ or H₂/Ni
  • describe how an amide forms when an acyl chloride and ammonia or an amine undergo condensation at room temperature
  • outline and account for the basicity shown by aqueous solutions of amines