BiologyCode 9700

Replication and division of nuclei and cells

What this topic asks you to be able to do

  • describe how a chromosome is built, limited to: its centromere and telomeres, its sister chromatids, and its DNA and histone proteins
  • account for why mitosis matters in producing genetically identical daughter cells when: multicellular organisms grow, damaged or dead cells are swapped for new ones, tissues are mended by replacing cells, asexual reproduction takes place
  • outline the course of the mitotic cell cycle, including: interphase (growth across the G1 and G2 phases, and copying of DNA in the S phase), mitosis, cytokinesis
  • outline how telomeres help stop genes being lost from the tips of chromosomes during DNA replication
  • outline what stem cells contribute to replacing cells and mending tissue through mitosis
  • account for the way that cell division running out of control can lead to a tumour forming